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Ausgewählte Publikationen aus den Jahren zwischen 1984 und 2015

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2014

Baumann, L., Knörr, S., Keiter, S., Rehberger, K., Volz, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Reversibility of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the estrogen 17α-ethinylestradiol. Toxicol. Appl. Phamracol. http://dx.doi.org/10.1016/j.taap.2014.04.025.

Busquet, F., Strecker, R., Rawlings, J.M., Belanger, S.E., Braunbeck, T., Carr, G.J., Cenijn, P., Fochtman, P., Gourmelon, A., Hübler, N., Kleensang, A., Knöbel, M., Kussatz, C., Legler, J., Lillicrap, A., Martínez-Jerónimo, F., Polleichtner, C., Rzodeczko, H., Salinas, E., Schneider, K.E., Scholz, S., van den Brandhof, E.-J., van der Ven, L.T.M., Walter-Rohde, S., Weigt, S., Witters, H. and Halder, M. (2014) OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing. Reg. Tox. Pharm. http://dx.doi.org/10.1016/j.yrtph.2014.05.018

Heinrich, P., Diehl, U., Förster, F. and Braunbeck, T. (2014) Improving the in vitro ethoxyresorufin-O-deethylase (EROD) assay with RTL-W1 by metabolic normalization and use of β-aphthoflavone as the reference substance. Comp. Biochem. Phys. 164C: 27-34. http://dx.doi.org/10.1016/j.cbpc.2014.04.005

Seiler, T.B., Best, N., Møller Fernqvist, M., Hercht, H., Smith, K.E.C., Braunbeck, T., Mayer, P. and Hollert, H. (2014) PAH toxicity at aqueous solubility in the fish embryo test with Danio rerio using passive dosing. Chemosphere 112: 77-84.

Seybold, B., Braunbeck, T. and Randler, C. (2014) Primate conservation − an evaluation of two different educational programs in Germany. Int. J. Sci. Math. Educ. 12: 285-305.

Baumann, L., Knörr, S., Keiter, S., Nagel, T., Rehberger,K., Volz, S., Oberrauch, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17ß-trenbolone. Environ. Toxicol. Chem. 33:2488-2496

Baumann, L., Knörr, S., Keiter, S., Nagel, T., Segner, H., Braunbeck, T. (2014a) Prochloraz causes irreversible masculinization of zebrafish (Danio rerio). Environ. Sci. Pollut. Res. DOI 10.1007/s11356-014-3486-3

Bluhm, K., Otte, J.C., Yang, L., Zinsmeister, C., Legradi, J., Keiter, S., Kosmehl, T., Braunbeck, T., Strähle, U., Hollert, H. (2014) Impacts of different exposure scenarios on transcript abundances in Danio rerio embryos when investigating the toxicological burden of riverine sediments. PLoS ONE 9(9): e106523. doi:10.1371/journal.pone.0106523

Braunbeck, T., Kais, B., Lammer, E., Otte, J., Schneider, K., Stengel, D., Strecker, R. (2014) The fish embryo test (FET): origin, applications, and future. Environ. Sci. Pollut. Res. DOI 10.1007/s11356-014-3814-7

Schulze, T., Ulrich, M., Maier, D., Maier, M., Terytze, K., Braunbeck, T., Hollert, H. (2014) Evaluation of the hazard potentials of river suspended particulate matter and floodplain soils in the Rhine basin using chemical analysis and in vitro bioassay. Environ. Sci. Pollut. Res. DOI 10.1007/s11356-014-3707-9

Vincze, K., Gehring, M., Braunbeck, T. (2014) (Eco)toxicological effects of 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) in zebrafish (Danio rerio) and permanent fish cell cultures. Environ. Sci. Pollut. Res. 21: 8233-8241

 

 

2013

Scholz, S., Sela, E., Blaha, L., Braunbeck, T., Galay-Burgos, M., García-Franco, M., Guinea, J., Klüver, N., Schirmer, K., Tanneberger, K., Tobor-Kaplon, M., Witters, H., Belanger, S., Benfenati, E., Creton, S., Cronin, M.T.D., Eggen, R.I.L., Embry, M., Ekman, D., Gourmelon, A., Halder, M., Hardy, B., Hartung, T., Hubesch, B., Jungmann, D., Lampi, M.A., Lee, L., Marc Léonard, M., Küster, E., Lillicrap, A., Luckenbach, T., Murk, A.J., Navas, J.M., Peijnenburg, W., Repetto, G., Salinas, E., Schüürmann, G., Spielmann, H., Tollefsen, K.E., Walter-Rohde, S., Whale, G., Wheeler, J.R., Winter, M.J. (2013) A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regul. Toxicol. Parmacol. 67: 506-530.

Otte, J.C., Keiter, S., Faßbender, F., Higley, E.B., Suares Rocha, P., Brinkmann, M., Wahrendorf, D.-S., Manz, W., Wetzel, M.A., Braunbeck, T., Giesy, J.-P., Hecker, M., Hollert, H. (2013) Contribution of priority PAHs and POPs to Ah receptor-mediated activities in sediment samples from the River Elbe Estuary, Germany. PLoS ONE 8(10): e75596.

Kais. B., Schneider, K.E., Keiter, S., Henn, K., Ackermann, C., Braunbeck, T. (2013) DMSO modifies the permeability of the zebrafish (Danio rerio) chorion – implications for the fish embryo test (FET). Aquat. Toxicol. 140-141: 229-238.

Braunbeck, T., Walter-Rohde, S. (2013) Fish Embryo Acute Toxicity Test with Zebrafish (ZFET). ECVAM DB-ALM, http://ecvam-dbalm.jrc.ec.europa.eu

Baumann, L., Holbech, H., Keiter, S., Lund Kinnberg, K., Knörr, S., Nagel., T. Braunbeck, T. (2013) The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test. Aquat. Toxicol. 128-129: 34-42.

Faßbender, C., Braunbeck, T. (2013a) Assessment of genotoxicity in gonads, liver and gills of zebrafish (Danio rerio) by use of the comet assay and micronucleus test after in vivo exposure to methyl methanesulfonate. Bull. Environ. Contam. Toxicol. 91: 89-95.

Faßbender, C., Braunbeck, T. (2013b) Reproductive and genotoxic effects in zebrafish after chronic exposure to methyl methanesulfonate in a multigeneration study. Ecotoxicology  DOI 10.1007/s10646-013-1057-x.

Strecker, R., Weigt, S., Braunbeck, T. (2013) Cartilage and bone malformations in the head of zebrafish (Danio rerio) embryos following exposure to disulfiram and acetic acid hydrazide. Toxicol. Appl. Pharmacol. 268: 221-231.

 

2012

Faßbender, C., Braunbeck, T., Keiter, S. (2012) Gene-TEQ – a standardized comparative assessment of effects in the comet assay using genotoxicity equivalents. J. Env. Monitor. 14: 1325-1334.177.    

Halder, M., Busquet, F., Amcoff, P., Gourmelon, A., Braunbeck, T., Belanger, S., Carr, G.J., Lillicrap, A. and Walter-Rohde, S. (2012) Validation report (phase 2) for the zebrafish embryo toxicity test. OECD Series on Testing and Assessment No. 179: 57 pp.

Halder, M., Busquet, F., Amcoff, P., Gourmelon, A., Braunbeck, T., Belanger, S., Carr, G.J., Lillicrap, A. and Walter-Rohde, S. (2012) Annexes to the validation report (phase 2) for the zebrafish embryo toxicity test. OECD Series on Testing and Assessment No. 179: 362 pp

Holbech, H., Kinnberg, K.L., Brande-Lavridsen, N., Bjerregaard, P., Petersen, G.I., Norrgren, L., Orn, S., Braunbeck, T., Baumann, L., Bomke, C., Dorgerloh, M., Bruns, E., Ruehl-Fehlert, C., Green, J.W., Springer, T.A., Gourmelon, A.  (2012) Comparison of zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) as test species in the Fish Sexual Development Test (FSDT). Comp. Biochem. Physiol. 155 C: 407-415.

Keiter, S., Baumann, L., Färber, H., Holbech, H., Skutlarek, D., Engwall, M., Braunbeck, T. (2012) Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). Aquat. Toxicol. 118-119: 116-129.

Kosmehl, T., Otte, J.E., Yang, L., Legradi, J., Bluhm, K., Zinsmeister, K., Keiter, S.H., Reifferscheid,  G., Manz, W., Braunbeck, T., Strähle, U., Hollert, H. (2012) A combined DNA-microarray and mechanism-specific toxicity approach with zebrafish embryos to investigate the pollution of river sediments. Reprod. Toxicol. 33: 254-253.

Peddinghaus, S., Brinkmann, M., Bluhm, K., Sagner, A., Hinger, G., Braunbeck, T., Eisenträger, A., Tiehm, A., Hollert, H., Keiter, S.H. (2012) Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio). Reprod. Toxicol. 33: 224-232.

Schmidt, F., Schnurr, S., Wolf, R., Braunbeck, T. (2012) Effects of the anti-thyroidal compound potassium-perchlorate on the thyroid system of the zebrafish. Aquat. Toxicol. 109: 47-58.

Schulze, T., Seiler, T.-B., Streck, G., Braunbeck, T., Hollert, H. (2012) Comparison of different exhaustive and biomimetic extraction techniques for chemical and biological analysis of polycyclic aromatic compounds in river sediments. J. Soils Sed. 12: 1419-1434.

 

2011

Boettcher, M., Kosmehl, T., Braunbeck, T. (2011) Low-dose effects and biphasic effect profiles: is trenbolone a genotoxicant? Mutat. Res. 723: 152-157.

Grund, S., Higley, E., Schönenberger, R., Suter, M.J.F., Giesy, J.P., Braunbeck, T., Hecker, M., Hollert, H. (2011) The endocrine disrupting potential of sediments from the Upper Danube River (Germany) as revealed by in vitro bioassays and chemical analysis. Environ. Sci. Pollut. Res. 18: 446-460.

Henn, K., Braunbeck, T. (2011) Dechorionation as a tool to improve the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Comp. Biochem. Physiol. 153C: 91-98.

Hinger, G., Brinkmann, M., Bluhm, K., Sagner, A., Takner, H., Eisenträger, A., Braunbeck, T., Engwall, M., Tiehm, A., Hollert, H. (2011) Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells. Environ. Sci. Pollut. Res. 18: 1297-1304.

Osterauer, M., Faßbender, C., Braunbeck, T., Köhler, H.-R. (2011) Genotoxicity of platinum in embryos of zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis). Sci. Toital Environ. 409: 2114-2119.

Rocha, P.S., Bernecker, C., Strecker, R., Mariani, C.F., Pompêo, M.L., Storch, V., Hollert, H., Braunbeck, T. (2011) Sediment-contact fish embryo toxicity assay with Danio rerio to assess particle-bound pollutants in the Tietê River Basin (São Paulo, Brazil). Ecotox. Environ. Safety 74: 1951-1959.

Schmidt, F., Braunbeck, T. (2011) Alterations along the hypothalamic-pituitary-thyroid axis of the zebrafish (Danio rerio) after exposure to propylthiouracil. J. Thyroid Res. doi:10.4061/2011/376243.

Schmidt, F., Schnurr, S., Wolf, R., Braunbeck T. (2011) Effects of the anti-thyroidal compound potassium-perchlorate on the thyroid system of the zebrafish. Aquat. Toxicol. 109C: 47-58.

Schweizer, N., Kummer, U., Hercht, H., Braunbeck T. (2011) Amplitude-encoded calcium oscillations in fish cells. Biophys Chem. 159: 294-302.

Strähle, U., Scholz, S., Geisler, R., Greiner, P., Hollert, H., Rastegar, S., Schumacher, A., Selderslaghs, I., Weiss, C., Witters, H., Braunbeck, T. (2011) Zebrafish embryos as an alternative to animal experiments. – A commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod Toxicol. 33: 128-132.

Strecker, R., Seiler, T.-B., Hollert, H., Braunbeck, T. (2011) Oxygen requirements of zebrafish (Danio rerio) embryos in embryo toxicity tests. Comp. Biochem. Physiol. 153C: 318-327.

Weigt, S., Huebler, N., Strecker, R., Braunbeck, T., Broschard, T.H. (2011a) Zebrafish (Danio rerio) embryos as a model for testing proteratogens. Toxicology 281: 25-36.

Weigt, S., Huebler, N., Strecker, R., Braunbeck, T., Broschard, T.H. (2011b) Developmental effects of coumarin and the anticoagulant coumarin derivative warfarin on zebrafish (Danio rerio) embryos. Reprod. Toxicol. 33: 133-141

Wetterauer, B., Ricking, M., Otte, J.C., Hallare, A.V., Rastall, A., Erdinger, L., Schwarzbauer, J., Braunbeck, T., Hollert, H. (2011) Toxicity, dioxin-like activities, and endocrine effects of DDT metabolites-DDA, DDMU, DDMS, and DDCN. Environ. Sci. Pollut. Res. 19: 403-415.

Wölz, J., Grosshans, K., Streck, G., Schulze, T., Rastall, A., Erdinger, L., Brack, W., Fleig, M., Kühlers, D., Braunbeck, T., Hollert, H. (2011) Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil - an approach combining tracer substance, bioassay and target analysis. Chemosphere 85: 717-723.

Zielke, H., Seiler, T.-B., Niebergall, S., Leist, E., Brinkmann, M., Spira, D. Streck, G., Brack, W., Feiler, U., Braunbeck, T., Hollert, H. (2011) The impact of extraction methodologies on the toxicity of sediments in the zebrafish (Danio rerio) embryo test. J. Soils Sed. 11: 352-363.

 

2010

Boettcher, M., Grund, S., Keiter, S., Kosmehl, T., Reifferscheid, G., Seitz, N., Rocha, P.S., Hollert, H., Braunbeck, T. (2010) Comparison of in vitro and in situ genotoxicity in the Danube River by means of the comet assay and the micronucleus test. Mutat. Res. 17: 11-17. [e-mail]

Braunbeck, T., Johnson, R., Wolf, J. (2010) Guidance document on the diagnosis of endocrine-related histopathology in fish gonads. Series on Testing and Assessment No. 123, 114 pp. [e-mail]

Embry, M.R., Belanger, S.E., Braunbeck, T., Galay-Burgos, M., Halder, M., Hinton, D.E., Léonard, M.A., Lillicrap, A., Norberg-King, T., Whale, G. (2010) The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research. Aquat. Toxicol. 97: 79 - 87. [e-mail]

Grund, G., Keiter, S., Böttcher, M., Seitz, N., Wurm, K., Manz, W., Hollert, H., Braunbeck, T. (2010) Assessment of fish health status in the Upper Danube River by investigation of ultrastructural alterations in the liver of barbel Barbus barbus. Dis. Aquat. Org. 88: 235 - 248. [e-mail]

Halder, M., Léonard, M., Iguchi, T., Oris, J.T., Ryder, K., Belanger, S.E., Braunbeck, T., Embry, M.R., Whale, G., Norberg-King, T., Lillicrap, A. (2010) Regulatory aspects on the use of fish embryos in environmental toxicology. Integr. Environ. Assess. Man. 6: 484-491.

Keiter, S., Peddinghaus, S., Feiler, U., von der Goltz, B., Hafner, C., Ho, N.Y., Rastegar, S., Otte, J.CV., Ottermanns, R., Reifferscheid, G., Strähle, U., Braunbeck, T., Hammers-Wirtz, M., Hollert, H. (2010a) DanTox – ein BMBF-Verbundprojekt zur Ermittlung spezifischer Toxizität und molekularer Wirkungsmechanismen sedimentgebundener Umweltschadstoffe mit dem Zebrabärbling (Danio rerio). Umweltwiss. Schadst. Forsch. 22: 94 - 98. [e-mail]

Keiter, S., Peddinghaus, S., Feiler, U., von der Goltz, B., Hafner, C., Ho, N.Y., Rastegar, S., Otte, J.CV., Ottermanns, R., Reifferscheid, G., Strähle, U., Braunbeck, T., Hammers-Wirtz, M., Hollert, H. (2010b) DanTox—a novel joint research project using zebrafish (Danio rerio) to identify specific toxicity and molecular modes of action of sediment-bound pollutants. J. Soils Sediments 10: 714 - 717. [e-mail]

Knacker, T., Boettcher, M., Frische, T., Rufli, H., Stolzenberg, H.C., Teigeler, M., Zok, S., Braunbeck, T., Schäfers, C. (2010) Environmental effect assessment for sexual endocrine-disrupting chemicals: Fish testing strategy. Integr. Environ. Assess. Manag. 6: 653-662.

Otte, J., Schmidt, A., Hollert, H., Braunbeck, T. (2010) Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio). Aquat. Toxicol. 100: 38-50. [e-mail]

Suares Rocha, P., Azab, E., Schmidt, B., Storch, V., Hollert, H., Braunbeck, T. (2010) Changes in toxicity and dioxin-like activity of sediments from the Tiete River (Sao Paulo, Brazil). Ecotoxicol. Environ. Safety 73: 550-558. [e-mail]

Ulrich, K., Wölfle, S., Mayer, A., Heeg, K., Braunbeck, T., Erdinger, L., Bartz, H. (2010) Extractable organic matter of standard reference material 1649a influences immunological response induced by pathogen-associated molecular patterns. Environ. Sci. Pollut. Res. 17: 1257-1267. [e-mail]

Weigt, S., Huebler, N., Braunbeck, T., von Landenberg, F., Broschard, T.H. (2010) Zebrafish teratogenicity test with metabolic activation (mDarT): Effects of phase I activation of acetaminophen on zebrafish Danio rerio embryos. Toxicology 275: 36-49. [e-mail]

Wolf, J., Johnson, R., Braunbeck, T. (2010) Guidance document on the diagnosis of endocrine-related histopathology in fish gonads. OECD Series on Testing and Assessment no. 123. OECD, Paris, ENV/JM/MONO(2010)14; 124 p.

Wölz, J., Brack, W., Moehlenkamp, C., Claus, E., Braunbeck, T., Hollert, H. (2010) Effect-directed analysis of Ah receptor-mediated activities caused by PAHs in suspended particulate matter sampled in flood events. Sci. Total Environ. 408: 3327 - 3333. [e-mail]

Wölz, J., Fleig, M., Schulze, T., Maletz, S., Lübcke von Varel, U., Reifferscheid, G., Kühlers, D., Braunbeck, T., Brack, W., Hollert, H. (2010) Impact of contaminants bound to suspended particulate matter in the context of flood events.  J. Soils Sed. 10: 1174-1185. [e-mail]

Wölz, J., Schulze, T., Lübcke-von Varel, U., Fleig, M., Reifferscheid, G., Brack, W., Kühlers, D., Braunbeck, T., Hollert, H. (2010) Investigation on soil contamination at recently inundated and non-inundated sites. J. Soils Sed. 11: 82-92.

 

2009

Braunbeck, T. (2009) Zebrafish embryos as a model in general toxicology. Toxicol. Lett. 189S: 548-549. [e-mail]

Braunbeck, T., Hollert, H., Brauns, A., Keiter, S., Schwartz, P. (2009) Fischpopulationen unter Stress – das Beispiel des Unteren Neckars. UWSF – Umweltwiss. Schadst. Forsch. 21: 197-211. [e-mail]

Grim, K.C., Wolfe, M., Braunbeck, T., Iguchi, T., Ohta, Y., Tooi, O., Touart, L., Wolf, D.C., Tietge, J.  (2009) Thyroid histopathology assessments for the amphibian metamorphosis sssay to detect thyroid-active substances. Toxicol. Pathol. 37: 415-424. [e-mail]

Hollert, H., Ernst, M., Ahlf, W., Dürr, M., Erdinger, L., Grund, S., Keiter, S., Kosmehl, T., Seiler, T.-B., Wölz, J., Braunbedck, T. (2009a) Strategien zur Sedimentbewertung – ein Überblick. UWSF – Umweltwiss. Schadst. Forsch. 21: 160-176. [e-mail]

Hollert, H., Claus, C., Ahlf, W., Brack, W., Braunbeck, T., Hudjetz, S., Manz, W., Ratte, H.-T., Reifferscheid, G., Schäffer, A., Schulze, T., Schwarzbauer, J, Heininger, P. (2009b) Über die Notwendigkeit der wirkungsorientierten Analytik in einer umfassenden Wasserforschung. UWSF – Umweltwiss. Schadst. Forsch. 21:235-237. [e-mail]

Keiter, S., Böttcher, M., Grund, S., Seitz, N., Braunbeck, T., Hollert, H. (2009a) Der Fischrückgang in der oberen Donau. UWSF – Umweltwiss. Schadst. Forsch. 21:186-196. [e-mail]

Keiter, S., Braunbeck, T., Heise, S., Pudenz, S., Manz, W., Hollert, H. (2009b) A fuzzy logic-classification of sediments based on data from in vitro biotests. J. Soils Sed. 9: 168-179. [e-mail]

Lammer, E., Carr, G.J., Wendler, K., Rawlings, J.M., Belanger, S.E., Braunbeck, T. (2009a) Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test? Compo. Biochem. Physiol. 149C: 196-209.  [e-mail]

Lammer, E., Kamp, H.G., Hisgen, V., Koch, M., Reinhard, D., Salinas, E.R., Wendler, K., Zok, S., Braunbeck, T. (2009b) Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicol. In Vitro 23: 1436-1442. [e-mail]

Opitz, R., Schmidt, F., Braunbeck, T., Wuertz, S., Kloas, W. (2009) Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis. Mol. Cell. Endocrinol. 298: 101 – 114. [e-mail]

Suares Rocha, P., Luvizotto, G.L., Kosmehl, T., Böttcher, M.  Storch, V., Braunbeck, T., Hollert, H. (2009) Sediment genotoxicity in the Tietê River(São Paulo, Brazil): In vitro comet assay versus in situ micronucleus assay studies. Ecotoxicol. Environ. Safety 72: 1842-1848.  [e-mail]

Weigt, S., Hubler, N., von Landenberg, F., Braunbeck, T., Broschard, T. (2009) Teratogenic effects of metabolically activated trimethadione in zebrafish (Danio rerio). Toxicol. Letters 189: S143. [e-mail]

 

2008

Keiter, S., Grund, S., Bavel, B., Hagberg, J., Engwall, M., Kammann, U., Klempt. M., Manz, W., Olsman, H., Braunbeck, T., Hollert, H. (2008) Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Anal. Bioanal. Chem. 390: 2009-2019.  [e-mail]

Kosmehl, T., Hallare, A.V., Braunbeck, T., Hollert, H. (2008) DNA damage induced by genotoxicants in zebrafish (Danio rerio) embryos after contact exposure to freeze-dried sediment and sediment extracts from Laguna Lake (The Philippines) as measured by the comet assay. Mutat. Res. 650: 1-14.  [e-mail]

Pluskota, B., Storch, V., Braunbeck, T., Beck, M., Becker, N. (2008) First record of Stegomyia albopicta (Skuse) (Diptera: Culicidae) in Germany. Eur. Mosq. Bull. 26, 1-5. [e-mail]

Seitz, N., Boettcher, M., Keiter, S., Manz, W., Hollert, H., Braunbeck, T. (2008) A novel statistical approach for the evaluation of comet assay data. Mutat. Res. 652: 38-45. [e-mail]

Weigt, S., Busquet, F., von Landenberg, F., Braunbeck, T., Huebler, N., Broschard, T.H. (2008) Application of human and rat liver microsomes in teratogenicity testing using zebrafish Danio rerio embryos (mDarT). Toxicol. Letters 180: S96-S97. [e-mail]

Wölz, J., Engwall, M., Maletz, S., Olsman Takner, H., Bavel, B., Kammann, U., Klempt, M., Weber, R., Braunbeck, T., Hollert, H. (2008) Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine – a mass balance approach using in vitro methods and chemical analysis. Environ. Sci. Poll. Res. 15: 536-553. [e-mail]

 

2007

Kosmehl, T., Krebs, F., Manz, W.,  Braunbeck, T., Hollert, H. (2007) Differentiation between bioavailable and total hazard potential of sediment-induced DNA fragmentation as measured by the comet assay with zebrafish embryos. J. Soils Sediments 7: 377-387. [e-mail]

 

2006

Keiter, S, Rastall, A., Kosmehl, T., Wurm, K., Erdinger, L., Braunbeck, T., Hollert, H. (2006): Ecotoxico­logical assessment of sediment, suspended matter and water samples in the upper Danube river. A pilot study in search for the causes for the decline of fish catches, Environ. Science Poll. Res. 13: 308-319. [e-mail]

Kosmehl, T., Reifferscheid, G., Manz, W., Braunbeck, T., Hollert, H. (2006): A novel contact assay to assess genotoxic burden of sediments using the comet assay with zebrafish larvae. Environ. Toxicol. Chem. 25: 2097-2106. [e-mail]

Opitz, R., Hartmann, S., Blank, T., Braunbeck, T., Lutz, I., Kloas, W. (2006) Evaluation of histological and molecular endpoints for enhanced detection of thyroid system disruption in Xenopus laevis tadpoles. Toxicol. Sci. 90: 337-348. [e-mail]

Seiler, T.B.Rastall, A., Leist, E., Erdinger, L., Braunbeck, T., Hollert, H. (2006) Membrane dialysis extraction (MDE): a novel approach for extracting toxicologically relevant hydrophobic organic compounds from soils and sediments for assessment in biotests. J. Soils Sed. 6: 20-29. [e-mail]

Suares Rocha, P., Keiter, S., Luiz Martins Pompêo, M., Fioriollo Mariani, C., Lúcia Brandimarte, A., Seiler, T.-B., Kosmehl, T., Böttcher, B., Wölz, J., Braunbeck, T., Storch, V., Hollert, H. (2006) Weight-of-Evidence-Studie zur Sedimentbelastung des Tietê River in Brasilien. UWSF B Z Umweltchem Ökotox 18: 70. [e-mail]

 

2005

Braunbeck, T., Böttcher, M., Hollert, H., Kosmehl, T., Lammer, E. Leist, E., Rudolf, R., Seitz, N. (2005) Towards an alternative for the acute fish LC50 test in chemical assessment: the fish embryo toxicity test goes multi-species B an update. ALTEX 22: 87-102. [e-mail]

Hollert, H., Dürr, M., Holtey-Weber, R., Islinger, M., Brack, W., Färber, H., Erdinger, L., Braunbeck, T. (2005): Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout - How explain deficiencies between bioanalytical effectiveness and chemically determined concentrations?  Environ. Science Poll. Res. 12: 347-360. [e-mail]

Opitz, R., Braunbeck, T., Bögi, C., Pickford, D.B., Nentwig, G., Oehlmann, J., Tooi, O., Lutz, I., Kloas, W. (2005) Description and initial evaluation of a Xenopus metamorphosis assay for detection of thyroid systemBdisrupting activities of environmental compounds. Environ. Toxicol. Chem. 24: 653-664. [e-mail]

 

2004

Diekmann, M., Waldmann, P., Schnurstein, A., Grummt, T., Braunbeck, T., Nagel, R. (2004) On the relevance of genotoxicity for fish populations II: Genotoxic effects in zebrafish (Danio rerio) exposed to 4-nitroquinoline-1-oxide in a complete life-cycle test. Aquat. Toxicol. 68: 27-37. [e-mail]

Klee, N., Gustavsson, L., Kosmehl, T., Engwall, M., Erdinger, L. Braunbeck, T., Hollert, H. (2004) Changes in toxicity and genotoxicity of industrial sewage sludge samples containing nitro- and amino-aromatic compounds following treatment in bioreactors with different oxygen regimes. Environ. Sci. Pollut. Res. 11: 313-320. [e-mail]

Kosmehl, T., Krebs, F., Manz, W., Erdinger, L., Braunbeck, T., Hollert, H. (2004) Comparative genotoxicity testing of Rhine river sediment extracts using the comet assay with permanent fish cell lines (RTG-2 and RTL-W1) and the Ames test. J. Soils Sed. 4: 84-94. [e-mail]

Pawlowski, S.,  Jakob, S., Patzewitz, E.M. Annosova, I., Sauer, A. Leist, E., Braunbeck, T. (2004) Ein außergewöhnliches Habitat des Tyrrhenischen Laubfrosches Hyla sarda DE BETTA, 1857, am Monte Orlano, Elba, Italien. Sauria 26: 33-40. [e-mail]

Pawlowski, S., Sauer, A., Shears, J.A., Tyler, C.R., Braunbeck, T. (2004) Androgenic and estrogenic effects of the synthetic androgen 17α-methyltestosterone on sexual development and reproductive performance in the fathead minnow (Pimephales promelas) determined using the gonadal recrudescence assay. Aquat. Toxicol. 68: 277-291. [e-mail]

Pawlowski, S., Ternes, T.A., Bonerz, M., Rastall, A.C., Erdinger, L., Braunbeck, T. (2004) Estrogenicity of solid phase-extracted water samples from two municipal sewage treatment plant effluents and river Rhine water using the yeast estrogen screen. Toxicol. in vitro 18: 129-138. [e-mail]

Pawlowski, S., van Aerle, R., Tyler, C.R., Braunbeck, T. (2004) Effects of 17α-ethinylestradiol in a fathead minnow (Pimephales promelas) gonadal recrudescence assay. Ecotox. Environ. Safety 57: 330-345. [e-mail]

 

2003

Braunbeck, T., Deventer, K., Eisenträger, A., Glück, U., Grummt, T., Gminski, R., Hansen, P.-D., Kramer, M., Mersch-Sundermann, V., Miltenburger, H.-G., Reifferscheid, G., Renberg, P., Schnurstein, A., Waldmann, P., Wittekindt, E., Zipperle, J. (2003) Gentoxizitätsprüfung im aquatischen Bereich B Möglichkeiten und Perspektiven. Vom Wasser 99: 137-232. [e-mail]

Castano,A., Bols, B., Braunbeck, T.,  Dierickx, P., Halder, M., Isomaa, B., Kawahara, K., Lee, L.E.J., Mothersill, C., Pärt, P., Repetto, G., Riego Sintes, J., Rufli, H., Smith, R., Wood, C., Segner, H. (2003) The use of fish cells in ecotoxicology B The report and recommendations of ECVAM workshop 47. ATLA 31: 317B351. [e-mail]

Hollert, H., Braunbeck, T.  (2003) Nachwuchsförderung in der Ökotoxikologie B New Blood in Ecotoxicology - UWSF B Z .Umweltchem. Ökotox .15: 281 B 282. [e-mail]

Hollert, H., Keiter, S., König, N., Rudolf, M., Ulrich, M., Braunbeck, T. (2003) A new sediment contact assay to assess particle-bound pollutants using zebrafish (Danio rerio) embryos. J. Soils  Sed. 3: 197-207. [e-mail]

Hollert, H., Haag, I., Dürr, M., Wetterauer, B., Holtey-Weber, R., Kern, U. Westrich, B., Färber, H., Erdinger, L., Braunbeck, T. (2003) Untersuchungen zum ökotoxikologischen Schädigungspoten­zial und Erosionsrisiko von kontaminierten Sedimenten in staugeregelten Flüssen. UWSF B Z. Umweltchem. Ökotox. 15: 5-12. [e-mail]

Islinger, M., Willimski, D., Völkl, A., Braunbeck, T. (2003) Effects of 17α-ethinylestradiol on the expression of three estrogen-regulated genes and cellular ultrastructure of liver and testes in male zebrafish. Aquat. Toxicol. 62: 85-103. [e-mail]

Pawlowski, S., Ternes, T., Bonerz, M., Kluczka, T., van der Burg, B., Nau, H., Erdinger, L., Braunbeck, T. (2003) Combined in situ and in vitro assessment of the estrogenic activity of sewage and surface water samples. Toxicol. Sci.75:57-65. [e-mail]

Schulze, T., Wetterauer, B., Schwarzbauer, J., Hollert, H.,  Braunbeck, T., Ricking, M. (2003) DDT und Metabolite in Sedimenten Berliner Gewässer: Vorkommen, Analytik und Schädigungspotential. UWSF Z. Umweltchem. Ökotox. 15: 71-77. [e-mail]

Segner, H., Braunbeck, T. (2003) End points for in vitro toxicity testing with fish cells. In: Mothersill, C., Austin, B. (eds.) In vitro methods in aquatic toxicology. Springer, Berlin, Heidelberg, pp. 77-142. [e-mail]

Triebskorn, R., Adam, S., Behrens, A., Beier, S., Böhmer, J., Braunbeck, T., Casper, H., Dietze, U., Gernhöfer, M., Honnen, W., Köhler, H.-R., Körner, W., Konradt, J., Lehmann, R., Luckenbach, T., Oberemm, A., Schwaiger, J., Segner, H., Strmac, M., Schüürmann, G., Siligato, S., Traunspurger, W. (2003) Establishing causality between pollution and effects at different levels of biological organization: the VALIMAR project. Human Ecol. Risk Assess. 9: 171-194. [e-mail]

Jobling, S., Casey, D., Rodgers-Gray, T., Oehlmann, J., Schulte-Oehlmann, U., Pawlowski, S., Braunbeck, T., Turner, A.P., Tyler, C.R. (2003) Comparative responses of molluscs and fish to environmental estrogens and an estrogenic effluent. Aquat. Toxicol. 65: 205-220. [e-mail]

 

2002

Ahlf, W., Braunbeck, T., Heise, S. , Hollert, H.  (2002) Sediment and soil quality criteria. In: Burton, F., McKelvie, I., Förstner, U., Guenther, A. (2002; eds.): Environmental monitoring handbook. McGraw-Hill, New York, pp. 17-18. [e-mail]

Braunbeck, T., Segner, H., Meinelt, T. (2002) Toxicological aspects of modern aquaculture. Revue Méd. Vét. 153: 521-522. [e-mail]

Hollert, H., Dürr, M., Olsman, H., Halldin, K., Bavel, B.v., Brack, W., Tysklind, M., Engwall, M., Braunbeck, T. (2002) Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the Neckar River. Ecotoxicology 11: 323-336. [e-mail]

Hollert, H., Heise, S., Pudenz, S., Brüggemann, R., Ahlf, W. and Braunbeck, T. (2002) Application of a sediment quality triad and different statistical approaches (hasse diagrams and fuzzy logic) for the comparative evaluation of small streams. Ecotoxicology 11: 311-321. [e-mail]

Islinger, M., Yuan, H., Völkl, A., Braunbeck, T. (2002) Measurement of vitellogenin gene expression by RT-PCR as a toll to identify endocrine disruption in Japanese medaka (Oryzias latipes). Biomarkers 7, 80-93. [e-mail]

Knörr, S., Braunbeck, T. (2002) Decline in reproduction success, sex reversal and developmental alterations in Japanese medaka (Oryzias latipes) after continuous exposure to octylphenol. Ecotox. Environ. Safety 51:187-196. [e-mail]

Schwaiger, J., Mallow, U., Ferling, H., Knoerr, S., Braunbeck, T., Kalbfus, W., Negele, R.D. (2002) How estrogenic is nonylphenol? A transgenerational study using rainbow trout (Oncorhynchus mykiss) as test organism. Aquat. Toxicol. 59: 177-189. [e-mail]

Strmac, M., Braunbeck, T. (2002) Cytological and biochemical effects of a mixture of 20 pollutants on isolated rainbow trout (Oncorhynchus mykiss) hepatocytes. Ecotox. Environ. Safety 53: 293-304. [e-mail]

Strmac, M., Oberemm, A., Braunbeck, T. (2002) Effects of sediment eluates and extracts from differently polluted small rivers on zebrafish embryos and larvae.  J. Fish Biol. 61: 24-38. [e-mail]

Ulrich, M., Schulze, T., Leist, E., Glaß, B., Maier, M., Maier, D., Braunbeck, T., Hollert, H. (2002) Ecotoxicological assessment of sediments and suspended particulate matter - potential risk of ground-water contamination and correlation of different exposure routes (organic extract, whole sediment) in the bacterial contact assay and the fish egg assay. UWSF B Z. Umweltchem. Ökotox. 14: 132-137. [e-mail]

 

2001

Braunbeck, T., Segner, H. (2001) Isolation and cultivation of teleost hepatocytes. In: Berry, M., Edwards, A.M. (2001, eds.) The hepatocyte review. Kluwer Acad. Publ., Dordrecht, Boston, London, pp. 49-72. [e-mail]

Braunbeck, T., Strmac, M. (2001) Assessment of water and sediment contamination in small streams by means of cytological and biochemical alterations in isolated rainbow trout (Oncorhynchus mykiss) hepatocytes. J. Aquat. Ecosys. Stress Recov. 8: 337-354. [e-mail]

Dietze, U., Braunbeck, T., Honnen, W., Köhler, H.-R., Schwaiger, J., Segner, H., Triebskorn, R., Schüürmann, G. (2001) Chemometric discrimination between streams based on chemical, limnological and biological data taken from freshwater fishes and their interrelationships. J. Aquat. Ecosys. Stress Recov. 8 319-336. [e-mail]

Hinton, D.E., Segner, H., Braunbeck, T. (2001) Toxic responses of the liver. In: Schlenk, D., Benson, W.H. (2001; eds.) Target organ toxicity in marine and freshwater teleosts. Taylor & Francis, London & New York, pp. 224-268. [e-mail]

Konradt, J., Braunbeck, T. (2001) Alterations of selected metabolic enzymes in fish following long-term exposure to contaminated streams. J. Aquat. Ecosys. Stress Recov. 8 299-318. [e-mail]

Schnurstein, A., Braunbeck, T. (2001) Tail moment versus tail length - application of an in vitro version of the comet assay in biomonitoring for genotoxicity in native surface waters using primary hepatocytes and gill cells from zebrafish (Danio rerio). Ecotox. Environ. Safety 49: 187-196. [e-mail]

Triebskorn, R., Böhmer, J., Braunbeck, T., Honnen, W., Köhler, H.-R., Lehmann, R., Oberemm, A., Schwaiger, J., Segner, H., Schüürmann, G., Traunspurger, W. (2001) The project VALIMAR (VALIdation of bioMARkers for the assessment of small stream pollution): objectives, experimental design, summary of results, and recommendations for the application of biomarkers in risk assessment. J. Aquat. Ecosys. Stress Recov. 8: 161-178. [e-mail]

 

2000

Braunbeck, T. (2000) Biotests with fish cell cultures - dreams and reality: Chances and limitations of alternatives to conventional toxicity tests with fish. In: Schöffl, H., Soielmann, H., Gruber, F.P., Appl, H., Harrer, F., Pfaller, W., Tritthart, H.A. (eds.) Forschung ohne Tierversuche 2000. Springer, Wien, New York, pp. 203-211. [e-mail]

Hollert, H., Dürr, M., Erdinger, L., Braunbeck, T. (2000) Cytotoxicity of settling particulate matter and sediments of the river Neckar (Germany) during a winter flood. Environ. Toxicol. Chem. 19: 528-534. [e-mail]

Pawlowski, S., Islinger, M., Völkl, A., Braunbeck, T. (2000) Temperature-dependent vitellogenin-mRNA expression in primary cultures of rainbow trout (Oncorhynchus mykiss) hepatocytes at 14 and 18 °C. Toxicol. in vitro 14: 531-540. [e-mail]

Strmac, M., Braunbeck, T. (2000) Isolated hepatocytes of rainbow trout (Oncorhynchus mykiss) as a tool to discriminate between differently contaminated small river systems.  Toxic. in Vitro 14: 361-377. [e-mail]

 

1999

Braunbeck, T. (1999) Chances and limitations of in vitro methods with fish cell cultures for the assessment of the toxicity of aquatic pollutants. Verh. Ges. Ichthyol. 1: 1-14. [e-mail]

Bieberstein, U., Braunbeck, T. (1999) Immunohistochemical localization of vitellogenin in rainbow trout (Oncorhynchus mykiss) hepatocytes using immunofluorescence. Sci. Total Environ. 233, 67-75. [e-mail]

Berbner, T., Rahman, N., Braunbeck, T. (1999) Induction of cytochrome P450 1A and DNA damage in isolated rainbow trout (Oncorhynchus mykiss) hepatocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biomarkers 4: 214-228. [e-mail]

Braunbeck, T., Appelbaum, S. (1999) Ultrastructural alterations in the liver and intestine of carp (Cyprinus carpio) induced by ultra-low peroral doses of endosulfan. Dis. aquat. Org. 36: 183-200. [e-mail]

Burkhardt-Holm, P., Oulmi, Y., Schroeder, A, Braunbeck, T. (1999) Toxicity of 4-chloro­ani­line in early life-stages of zebrafish (Brachydanio rerio): II. Cytopathology of liver and gills after exposure to water-borne 4-chloroaniline. Arch. Environ. Contam. Toxicol. 37: 85-102. [e-mail]

Hollert, H., Dürr, M., Geier, V., Braunbeck, T. (1999) Ökotoxikologie in vitro: Gefährdungspoten­tial in Neckarsedimenten. In: Oehlmann, J., Markert, B. (eds.) Ökotoxikologie - Ökosystemare Ansätze und Methoden. Ecomed, Landsberg, pp. 444-462. [e-mail]

Islinger, M., Pawlowski, S., Hollert, H., Völkl, A., Braunbeck, T. (1999) Measurement of vitellogenin-mRNA expression in primary cultures of rainbow trout hepatocytes in a non-radioactive dot blot/RNAse protection-assay. Sci. Total. Environ. 233, 109-122. [e-mail]

Knörr, S., Bohl, M., Braunbeck, T. (1999) Die Entwicklung roter und weißer Muskulatur bei juvenilen Huchen (Hucho hucho) unter dem Einfluss unterschiedlicher Strömung S ein Beitrag zur Optimierung der Kondition zur Ausbürgerung in natürliche Habitate.  Verh. Ges. Ichthyol. 1: 109-127. [e-mail]

Strmac, M., Braunbeck, T. (1999) Effects of triphenyltin acetate on early life-stages of zebrafish (Danio rerio). Ecotox. Environ. Safety 44: 25-39. [e-mail]

Schramm, M., Behrens, A., Braunbeck, T., Eckwert, H., Köhler, H.-R., Konradt, J., Müller, E., Pawert, M., Schwaiger, J., Segner, H., Triebskorn, R. (1999) Cellular, histological and biochemical biomarkers. In: Gerhardt, A. (ed.) Biomonitoring of polluted water - reviews on actual topics. Environ. Science Forum 96; Trans Tech Publ., Uetikon-Zürich, pp. 33-64. [e-mail]

Triebskorn, R., Adam, S., Behrens, A., Braunbeck, T., Gränzer, S., Honnen, W., Konradt, J., Köhler, H.-R., Oberemm, A., Pawert, M., Schlegel, T., Schramm, M., Schüürmann, G., Schwaiger, J., Segner, H., Strmac, M., Müller, E. (1999) Eignung von Biomarkern zur Fließgewässerbewertung: Zwischenergebnisse aus dem Projekt `ValimarA (1995-1997). In: Oehlmann, J., Markert, B. (eds.) Ökotoxikologie - Ökosystemare Ansätze und Methoden. Ecomed, Landsberg, pp. 399-407. [e-mail]

 

1998

Bieberstein, U., Braunbeck, T. (1998) Light and scanning electron microscopic cytopathology of 3,5-dichloro­phenol in the permanent fish cell line RTG-2. Ecotox. Environ. Safety 41: 298-306. [e-mail]

Braunbeck, T. (1998) Cytological alterations in fish hepatocytes following in vivo and in vitro sublethal exposure to xenobiotics – structural biomarkers of environmental contamination. In: Braunbeck, T., Hinton, D.E., Streit, B. (eds.) Fish ecotoxicology. Birkhäuser, Basel, pp. 61-140. [e-mail]

Feldhusen, F., Braunbeck, T., Wallner, F. (1999) Dysphagia after eating sea foods. Pyriform sinus foreign body with perforation and abscess of the parapharyngeal space. HNO 47: 746-747. [e-mail]

Hollert, H., Dürr, M., Erdinger, L., Braunbeck, T. (1998) Wie giftig sind Schadstoffe und Sedimente des Neckars? Zur Eignung von Biotests und Bioassay-dirigierten Fraktionierungstechniken für die Bewertung des Schadstoffpotentials in hydrologischen Fallstudien. J. Heidelberger Geograph. Ges. 13: 130-145. [e-mail]

Scholz, S., Braunbeck, T., Segner, T. (1998) Viability and differential function of rainbow trout hepatocytes in primary culture: the influence of culture conditions. In Vitro Cell. Dev. Biol. 34: 762-771. [e-mail]

Segner, H., Braunbeck, T. (1998) Cellular response profile to chemical stress. In: Schüürmann, G., Markert, B. (eds.) Ecotoxicology. Wiley, J. & Sons, Inc. and Spektrum Akademischer Verlag, pp. 521-569. [e-mail]

 

1997

Braunbeck, T. (1997) Alternative methods in aquatic ecotoxicology. Eco-Informa 12:446-451. [e-mail]

Braunbeck, T., Hollert, H., Dürr, M., Erdinger, L.F. (1997) Biotests in der Ökotoxikologie am Beispiel des Fischzelltests. Veröff. PAÖ 22: 241-256. [e-mail]

Hofer, R., Köck, G., Braunbeck, T. (1997) Nuclear alterations in hepatocytes of Arctic char Salvelinus alpinus from acidic high alpine lakes. Dis. aquat. Org. 28: 139-150. [e-mail]

Moutou, K.A., Braunbeck, T., Houlihan, D.F. (1997) Quantitative analysis of alterations in liver ultrastructure of rainbow trout Oncorhynchus mykiss after administration of the aquaculture antibacterials oxolinic acid and flumequine. Dis. Aquat. Org. 29: 21-34.b [e-mail]

Zanger, M., Gräff, S., Braunbeck, T., Alberti, G., Köhler, H.-R. (1997) Detection and induction of cytochrome P450IA (CYP 1A)-like proteins in Julus scandinavius (Diplopoda) and Oniscus asellus (Isopoda): A first analysis. Bull. Environ. Contam. Toxicol. 58: 511-517. [e-mail]

Scholz, S., Behn, I., Honeck, H., Hauck, C., Braunbeck, T., Segner, H. (1997) Development of a monoclonal antibody for ELISA of CYP1A in primary cultures of rainbow trout (Oncorhynchus mykiss) hepatocytes. Biomarkers 2: 287-294. [e-mail]

 

1996

Arnold, H., Pluta, H.-J., Braunbeck, T. (1996a) Cytological alterations in the liver of rainbow trout Oncorhynchus mykiss after prolonged exposure to low concentrations of waterborne endosulfan. Dis. aquat. Org. 25: 39-52. [e-mail]

Arnold, H., Pluta, H.-J., Braunbeck, T. (1996b) Sublethal effects of prolonged exposure to disulfoton in rainbow trout (Oncorhynchus mykiss): cytological alterations in the liver by a potent acetylcholine esterase inhibitor. Ecotox. Environ. Safety 34: 43-55. [e-mail]

Oulmi, Y, Braunbeck, T. (1996) Toxicity of 4-chloroaniline in early life-stages of zebrafish (Brachydanio rerio): I. Cytopathology of liver and kidney after microinjection. Arch. Environ. Contam. Toxicol. 30: 390-402. [e-mail]

Zahn, T., Arnold, H., Braunbeck, T. (1996) Cytological and biochemical response of R1 cells and isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) to subacute in vitro exposure to disulfoton. Exp. Toxicol. Pathol. 48: 47-64. [e-mail]

 

1995

Arnold, H., Pluta, H.-J., Braunbeck, T. (1995) Simultaneous exposure of fish to endosulfan and disulfoton in vivo: ultrastructural, stereological and biochemical reactions in hepatocytes of male rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 33: 17-43. [e-mail]

Braunbeck, T., Berbner, T., Bieberstein, U., Erdinger, L., Geier, V., Hollert, H., Leist, E., Rahman, N., Zipperle, J.  (1995) Toxikologische und ökotoxikologische Untersuchung und Bewertung verschiedener Komparti­men­te in Fließgewässern mit Hilfe eines mehrstufigen Prüfsystems mit Zellkulturen aus Fischen. PAÖ 12: 345-358. [e-mail]

Braunbeck, T., Hauck, C., Scholz, S., Segner, H. (1995) Mixed function oxygenases in cultured fish cells: contributions of in vitro studies to the understanding of MFO induction. Z. angew. Zool. 81: 55-72. [e-mail]

Hollert, H., Dürr, M., Dörr, I., Erdinger, L.F., Zipperle, J., Braunbeck, T. (1996) Toxikologische und ökotoxikologische Untersuchung und Bewertung der Komparti­men­te in Fließgewässern mit Hilfe von Zellkulturen aus Fischen. Veröff. PAÖ 16: 469-488. [e-mail]

Oulmi, Y., Negele, R.-D., Braunbeck, T. (1995) Segment specificity of the cytological re­spon­se in rain­bow trout (Onco­rhynchus mykiss) renal tubules following prolonged exposure to sub­lethal con­cen­tra­tions of atrazine. Ecotox. Environ. Safety 32: 39-50. [e-mail]

Oulmi, Y., Negele, R.-D., Braunbeck, T. (1995) Cytopathology of liver and kidney in rain­bow trout Oncorhyn­chus mykiss after long-term exposure to sublethal concentra­tions of linuron. Dis. aquat. Org. 21: 35-52. [e-mail]

Zahn, T., Hauck, C., Holzschuh, J., Braunbeck, T. (1995) Acute and sublethal toxicity of seepage waters from garbage dumps to permanent cell lines and primary cultures of hepatocytes from rainbow trout (Oncorhynchus mykiss): a novel approach to environmental risk assessment for chemicals and chemical mixtures. Zbl. Hyg. 196: 455-479. [e-mail]

Zahn, T., Braunbeck, T. (1995) Cytotoxic effects of sublethal concentrations of malachite green in isolated hepatocytes from rainbow trout (Oncorhynchus mykiss). Toxic. in Vitro 9: 729-741. [e-mail]

 

1994

Arnold, H., Braunbeck, T. (1994) Disulfoton as a major toxicant in the Rhine chemical spill at Basle in 1986: acute and chronic studies with eel and rainbow trout. In: Müller R, Lloyd R (eds.) Sublethal and chronic effects of pollutants on freshwater fish. Blackwell, Oxford, pp. 75-87. [e-mail]

Braunbeck, T. (1994a) Entwicklung von Biotestverfahren mit Zellkulturen aus Fischen zum Nachweis letaler und subletaler Schäden von Organismen durch Um­weltschadstoffe im Wasser. – Zelluläre Biomarker in Fischzellkulturen. PAÖ 8: 533-558. [e-mail]

Braunbeck, T. (1994b)  Detection of environmentally relevant concentrations of toxic organic compounds using histological and cytological parameters: substance-specificity in the reaction of rainbow trout liver? In: Müller, R., Lloyd, R. (eds.) Sublethal and chronic effects of pollutants on freshwater fish. Blackwell, Oxford, pp. 15-29. [e-mail]

Phromkunthong, W., Storch, V., Braunbeck, T. (1994) Sexual dimorphism in the reaction of zebrafish (Brachydanio rerio) to as­cor­bic acid defi­cien­cy: Induction of steatosis in hepatocytes of male fish. J. Appl. Ichthyol. 10: 146-153. [e-mail]

Schmidt, H., Ritter, G., Ruider, S., Schmahl, G., Mehlhorn, H., Braunbeck, T. (1994) Administra­tion of a medicated food containing malachite green for the control of ectoparasitic diseases of ornamental fish. Mem. Inst. Océano. P. Ricard, Leipzig 1994, 57-61. [e-mail]

Triebskorn, R., Köhler, H.-R., Flemming, J., Braunbeck,  T., Negele, R.D., Rahmann, H. (1994) Evaluation of bis(tri-n-butyltin)oxide (TBTO) neurotoxicity in rainbow trout (Oncorhynchus mykiss). I. Behaviour, weight increase, and tin content. Aquat. Toxicol. 30: 189-197 [e-mail]

Triebskorn, R., Köhler, H.R., Körtje, K.H., Negele, R.D., Rahmann, H., Braunbeck, T. (1994) Evaluation of bis(tri-n-butyltin)oxide (TBTO) neurotoxicity in rainbow trout (On­co­rhynchus mykiss). II. Ultrastructural diagnosis and tin localization by energy filtering transmission electron micros­copy (EFTEM). Aquat. Toxicol. 30: 199-213. [e-mail]

 

1993

Braunbeck, T. (1993a) Cytological alterations in isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) exposed in vitro to 4-chloroaniline. Aquat. Toxicol. 25: 83-110. [e-mail]

Braunbeck, T. (1993b) Entwicklung von Biotestverfahren mit Zellkulturen aus Fischen und Mollusken zum Nachweis letaler und subletaler Schäden von Organismen durch Umweltschadstoffe im Wasser. PAÖ 7: 537-559. [e-mail]

Braunbeck, T., Völkl, A. (1993) Toxicant-induced cytological alterations in fish liver as biomarkers of environmental pollution? A case study on hepatocellular effects of dinitro-o-cresol in golden ide (Leu­cis­cus idus melanotus). In: Braunbeck, T., Hanke, W., Segner, H. (eds.) Fish - Ecotoxicology and Ecophysiolo­gy, VCH, Weinheim, pp. 55-80. [e-mail]

Braunbeck, T., Hauck, C., Zahn, T. (1993) Primärzellkulturen aus Fischhepatocyten als alternatives Testsystem in der ökotoxikologischen Forschung. In: Hardegg, W., Livaditis, I., Vogt, M. (eds.) Tierschutz durch Alternativen. Verlag Gesundheit, Berlin, pp. 243-247. [e-mail]

Lester, S.M., Braunbeck, T., Teh, S.J., Stegeman, J.J., Miller, M.R., Hinton, D.E. (1993) Hepatic cellular distribution of cytochrome P-450 IA1 in rainbow trout (Oncorhynchus mykiss): an immunohisto- and cytochemical study. Cancer Res. 53, 3700-3706. [e-mail]

Zahn, T., Braunbeck, T. (1993) Isolated fish hepa­tocy­tes as a tool in aquatic toxicology: sublethal effects of dinitro-o-cresol and 2,4-dichloro­phenol. Sci. Total Environ. Suppl., pp. 721-734. [e-mail]

Zahn, T., Hauck, C., Braunbeck, T. (1993a) Fischfibrocyten als alternatives Testsystem: Untersuchung subletaler Effekte umweltrelevanter Schadstoffe mit R1-Zellen. In: Hardegg, W., Livaditis, I., Vogt, M. (eds.) Tierschutz durch Alternativen. Verlag Gesundheit, Berlin, pp. 301-306. [e-mail]

Zahn, T., Hauck, C., Braunbeck, T. (1993) Cytological altera­tions in fish fibrocytic R1 cells as an alternative test system for the detection of sublethal effects of environ­mental pollutants: a case-study with 4-chloroaniline. In: Braun­beck, T., Hanke, W., Segner, H. (eds.) Fish - Ecotoxico­logy and Ecophysiology, VCH, Weinheim, pp. 103-126. [e-mail]

 

1992

Braunbeck, T. (1992) Isolierte Hepatocyten und Dauerzellinien aus Fischen im Cytotoxizitätstest – eine Alternative zur Fischleberzelle in vivo? In: Schöffl, H., Schulte-Hermann, R., Tritthart, H.A. (eds.) Möglichkeiten und Grenzen der Reduktion von Tierversuchen. Springer Verlag, Wien,  New York, pp. 153-154. [e-mail]

Braunbeck, T., Segner, H. (1992) Preexposure temperature acclimation and diet as mo­di­fy­ing fac­­tors for the tolerance of golden ide (Leuciscus idus melanotus) to short-term exposure to 4-chloroaniline. Ecotox. Environ. Safety 24: 72-94. [e-mail]

Braunbeck, T., Storch, V. (1992) Senescence of hepatocytes isolated from rainbow trout (Onco­rhyn­chus mykiss) in primary culture. An ultrastructural study. Protoplasma 170: 138-159. [e-mail]

Braunbeck, T., Burkhardt-Holm, P., Görge, G., Nagel, R., Negele, R.-D., Storch, V. (1992) Re­gen­bo­gen­forelle und Zebrabärbling, zwei Modelle für verlängerte Toxizitätstests: Relative Empfindlich­keit, Art- und Organspezifität in der cytopa­thologischen Reaktion von Leber und Darm auf Atra­zin. Schriftenr. Ver. Wasser Boden Lufthyg. 89: 109-145. [e-mail]

Braunbeck, T., Teh, S.J., Lester, S.M., Hinton, D.E. (1992) Ul­trastructural alterations in hepato­cytes in liver of medaka (Oryzias latipes) exposed to diethylnitros­amine. Toxicol. Pathol. 20: 179-196. [e-mail]

Lester, S.M., Braunbeck, T., Teh, S.J., Stegeman, J.J., Miller, M.R., Hinton, D.E. (1992) Immunocytochem­ical localization of cytochrome P 450 1A1 in liver of rainbow trout (Oncorhynch­us mykiss). Mar. Environ. Res. 34: 117-122. [e-mail]

Spazier, E., Storch, V., Braunbeck, T. (1992) Cytopathology of spleen in eel Anguilla an­guil­la exposed to a chemical spill in the Rhine river. Dis. aquat. Org. 14: 1-22. [e-mail]

 

1991

Braunbeck, T., Völkl, A. (1991) Induction of biotransformation in the liver of eel (An­guil­la an­guil­la L.) by sublethal exposure to dinitro-o-cresol: An ul­trastructural and bio­chemical study. Ecotox. Environ. Safety 21: 109-127. [e-mail]

 

1990

Braunbeck, T., Storch, V., Bresch, H. (1990) Species-specific reaction of li­ver ul­­trastruc­ture in zebra fish (Brachydanio rerio) and trout (Salmo gaird­neri) after pro­­longed exposure to 4-chloroaniline. Arch. Environ. Con­tam. Toxicol. 19: 405-418. [e-mail]

Braunbeck, T., Burkhardt-Holm, P., Storch, V. (1990) Liver pathology in eels (Anguilla an­guilla L.) from the Rhine river exposed to the chemical spill at Basle in November 1986. Limnologie  aktuell 1: 371-392. [e-mail]

Braunbeck, T., Görge, G., Storch, V., Nagel, R. (1990) Hepatic steatosis in zebra­ fish (Brachy­danio rerio) induced by long-term exposure to γ-hexachlorocyclo­hexane. Ecotox. Environ. Safety 19: 355-374. [e-mail]

Segner, H., Braunbeck, T. (1990a) Adaptive changes of liver composition and structure in golden ide during winter acclimatization. J. Exp. Zool. 255: 171-185. [e-mail]

Segner, H., Braunbeck, T. (1990b) Qualitative and quantitative assessment of the response of milk­fish, Chanos chanos, fry to low-level copper ex­po­sure. In: Perkins, F., Cheng, T.C. (eds.) Pa­tho­logy in Marine Science (Procee­dings of PAMAQ III, Gloucester Point, Virginia), pp. 347-368. [e-mail]

Segner, H., Braunbeck, T. (1990c) Qualitative and quantitative assessment of the response of milk­fish, Chanos chanos, fry to low-level copper ex­po­sure. In: Perkins, F.O., Cheng, T.C. (eds.) Pa­tho­logy in Marine Science (Proc. PAMAQ III, Gloucester Point, Virginia), pp. 347-368. [e-mail]

Burkhardt-Holm, P., Braunbeck, T., Storch, V. (1990) Aus­wir­kung der beim San­­doz-Un­fall im No­vember 1986 in den Rhein ge­langten Chemika­lien auf die Ultra­struktur des Darms von Aalen. Limnologie aktuell 1: 393-404. [e-mail]

 

1989

Braunbeck, T., Nagel, R., Storch, V. (1989) Sex-specific reaction of liver ul­tra­structure in zebra fish (Brachydanio rerio) after prolonged sub­lethal exposure to 4-nitrophe­nol. Aquat. Toxicol. 14: 185-202. [e-mail]

Storch, V., Braunbeck, T., Waitkuwait, W.-E. (1989) The liver of the West Af­ri­­can cro­co­dile Osteolaemus tetraspis:An ultrastructural study. J. Submicr. Cytol. Pathol. 21: 317-327. [e-mail]

Braunbeck, T., Storch, V. (1989) Zelle und Umwelt: Wie wirken sich Um­welt­­­gif­te auf Zel­len aus? Biologie in unserer Zeit 89/4: 127-132.

Braunbeck, T., Bresch, H., Nagel, R. (1989) Stoffspezifische Reaktionen der Ultrastruktur der Le­­ber des Zebra­bärb­lings (Brachydanio rerio) auf Chemikalien. Verh. Dt. Zool. Ges. 82: 183.

 

1988

Rafael, J., Braunbeck, T. (1988) Interacting effects of diet and environmental tempera­ture on bio­chem­ical para­meters in the liver of Leuciscus idus melanotus (Cy­pri­ni­dae: Teleostei). Fish Physiol. Biochem. 5: 9-19. [e-mail]

Segner, H., Braunbeck, T. (1988) Hepatocellular adaptation to extreme nu­tri­­tion­al cond­i­tions in ide, Leuciscus idus melanotus L. (Cypri­nidae). A mor­pho­functional analysis. Fish Physiol. Bio­chem. 5: 79-97. [e-mail]

 

vor 1988

Braunbeck, T., Dales, R.P. (1984) The role of the heart-body and of the ex­tra­vasal tissue in disposal of foreign cells in two polychaete annelids. Tissue & Cell 16: 557-563. [e-mail]

Braunbeck, T., Dales, R.P. (1985) The ultrastructure of the heart-body and ex­tra­vasal tissue in the poly­chaete annelids Neoamphitrite figulus and Arenicola marina. J. mar. biol. Ass. U.K. 65: 653-662. [e-mail]

Braunbeck, T. , Gorgas, K., Storch, V., Völkl, A. (1987) Ultrastructure of he­pa­to­cytes in golden ide (Leuciscus idus melanotus L.; Cyprinidae: Teleostei) during thermal adap­t­ation. Anat. Embryol. 175: 303-313. [e-mail]